Mervyn Miles describes developments towards high-speed non-contact atomic force microscopy for studying living cells.

Mervyn Miles is Professor of Physics, Head of the Nanophysics and Soft Matter Group, and Director of the Centre for Nanoscience & Quantum Information at the University of Bristol. His research activity over the last 20 years has been in the development and application of new scanning probe microscopes (SPM) with specific applications in soft matter. His current research focuses on atomic force microscopy (AFM), scanning tunnelling microscopy, scanning near-field optical microscopy, high-speed AFM, high-speed non-contact AFM, holographic optical tweezers, optical AFM, polymers, biomolecules.

Miles is also Chief Scientific Advisor for IOP Publishing and a Board Member and Section Editor of the journal Nanotechnology.

Further reading

Scanning Probe Evolution in Biology Hörber J K H and Miles M J 2003 Science 302, 1002-1005

A mechanical microscope: High-speed atomic force microscopy Humphris A D L, Miles M J and Hobbs J K 2005 Applied Physics Letters 86, 034106

Breaking the speed limit with atomic force microscopy Picco L M et al. 2007 Nanotechnology 18, 044030

High-speed atomic force microscopy in slow motion - Understanding cantilever behaviour at high scan velocities Payton O D et al. 2012 Nanotechnology 23 205704

Methods for imaging DNA in liquid with lateral molecular-force microscopy Harniman R L et al. 2012 Nanotechnology 23, 085703

Self-assembling cages from coiled-coil peptide modules Jordan M et al. 2013 Science 340, 595

Shape-induced force fields in optical trapping Phillips D B et al. 2014 Nature Photonics 8, 400-405