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Technology update

Feb 20, 2007

Nanoholes detect cancer antigens

According to work by researchers in the US, nanosized holes in ultrathin gold films on glass can be used as biochemical sensors. The new technique, which does not require labelling of the biomolecules as in some current sensing methods, works by measuring the changes in the so-called surface plasmon resonance (SPR) peak in the absorption spectrum of light passing through the holes. It can be used to selectively sense cancer antigens down to the picogram level once the gold and glass surfaces have been modified with bioreceptors.

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