Remotely triggered release
Remotely triggered release from nanoparticles in vivo.
Nanoparticles were mixed with matrigel and injected subcutaneously near the posterior
mammary fat pad of mice, forming model tumours (A). Application of EMF to implants containing 18 bp tethers resulted in release of model drugs
and penetration far into surrounding tissue (B) when compared to unexposed controls (C, scale bar = 100 microns). These mice were imaged
with a 7T MRI scanner, and transverse section shown in (D) depicts image contrast due to presence of nanoparticles (arrow). Credit: Adv. Mat..