Differential centrifugal sedimentation (DCS) is a novel and innovative, yet simple technique, which has become ‘reborn’ in recent years. Previous limitations and difficulties with the technique of sedimentation have been overcome using recent advances in technology, and some smart thinking regards instrumentation and disc design. DCS is now a powerful tool in measuring nano particle size distributions down to around 2nm. With the unique ability to resolve very close multi-modal particle distributions, and to distinguish extremely small shifts and changes in particle size, DCS is once more gaining in popularity. The practical range of the technique is from around 2nm right up to 80 micron (exact range will be dependent on density) , however the real benefits over and above more traditional so-called nano particle sizing techniques are generally noticed below around 300nm…

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